Isolation of Proteins which Interact with Phospholipase A2 (IIA) from Human Serum after Myocardial Infarction. Flavonoids from Bidens tripartita Extract as Phospholipase A2 Inhibitors
نویسندگان
چکیده
منابع مشابه
Serum secretory phospholipase A2-IIa (sPLA2-IIA) levels in patients surviving acute myocardial infarction.
BACKGROUND The increase of secretory phospholipase A2-IIa (sPLA2-IIa) in culprit coronary lesions is associated with myocardial infarction, and the increase of sPLA2-IIa in peripheral plasma levels has a significant risk and prognostic value in patients with coronary artery disease. Little is known about the prognostic significance of elevated serum sPLA2-IIa in post-acute myocardial infarction...
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Phospholipase A2 values increase in serum in various inflammatory states, infections, and postoperatively in surgical patients. Several organs, including the liver and spleen have been suggested as sources of circulating phospholipase A2. The purpose of the present work was to examine the possible role of the spleen as a source of elevated serum concentrations of phospholipase A2 after surgery....
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The purpose of this study was to define the role of secretory phospholipase A2 (sPLA2), calcium-independent PLA2, and cytosolic PLA2 (cPLA2) in arachidonic acid (AA) release from fMLP-stimulated human neutrophils. While fMLP induced the release of extracellular sPLA2 activity and AA, 70% of sPLA2 activity remained associated with the cell. Treatment with the cell-impermeable sPLA2 inhibitors DT...
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conclusions sch is associated with increased level of pla2-iia, which is independent of bmi. the stronger association of sch with pla2-iia than with hs-crp indicates that pla2-iia is an inducer of inflammation while hs-crp is not. results serum levels of tg, cholesterol, and ldl were higher in the sch group than the control group. however, there was no significant difference between the two gro...
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ژورنال
عنوان ژورنال: Environmental Research, Engineering and Management
سال: 2017
ISSN: 2029-2139,1392-1649
DOI: 10.5755/j01.erem.72.4.16494